Neuron· Adam G. Gordon, Barbara M. Benowitz, Joumana M. Barbakh, Isabella Montequin, Anthony Campuzano, Hannah P. Stevenson, Pei-Yun Lu, Madelyn M. Hjort, Ethan Ancell, Madalyn Critz, Daniela Witten, Garret D. Stuber·· 28 天前AI 评分73
外侧下丘脑调控摄食行为中纹状体多巴胺释放模式
Lateral hypothalamic control of the striatal dopamine landscape during consummatory behavior
AI 导读
依据期刊摘要，Gordon 等人发现外侧下丘脑的 GABA 与谷氨酸神经元协同作用，在摄食过程中调节纹状体各区域的多巴胺释放。该多巴胺释放模式会随动物所摄入的内容而变化，其作用被描述为促使动物重新开始摄食，而非延长单次摄食时间。材料仅为摘要，未提供样本量、实验设计与统计结果，相关机制是否适用于人类尚不明确。
摘要
Gordon et al. find that GABA and glutamate neurons in the lateral hypothalamus act together as a mechanism that tunes dopamine release across the striatum during consumption. This dopamine pattern shifts with what an animal is consuming, pushing it to start again rather than to keep consuming longer.
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来源：Neuron · cell.com